B vitamins increase Nitric Oxide production by reducing homocysteine levels in the blood.
Elevated homocysteine levels inhibit the arginine-NO pathway and prevent Nitric Oxide production. Because of this, most Nitric Oxide supplements do not produce results.
Many studies have shown that homocysteine levels inhibit NO synthase. This occurs because homocysteine increases plasma levels of asymmetric dimethylarginine (ADMA), an inhibitor of nitric oxide.
The rise in plasma ADMA causes a reduced activity of dimethylarginine dimethylaminohydrolase (DDAH), the enzyme that degrades ADMA. Furthermore, homocysteine-induced accumulation of ADMA causes reduced nitric oxide synthesis. The powerful antioxidant impact of the family of B vitamins preserves DDAH activity and inhibits ADMA accumulation. Moreover, homocysteine dose-dependently reduces the activity of recombinant human DDAH, an effect of direct interaction between homocysteine and DDAH.
Homocysteine inhibits DDAH enzyme activity, causing ADMA to accumulate and inhibit nitric oxide synthesis. In short, NO is of little value, whether taken in supplement form or produced from the endothelial cell, in the presence of elevated homocysteine levels.
COR-Restor contains potent B vitamins that produce the greatest bio-availability of NO. In fact, COR-Restor's B vitamins improve the effectiveness of statin medication and inhibit the reduction of CoQ10 caused by statin drugs and ADMA levels, allowing for better treatment.
Vitamin B3 goes a step further by increasing HDL cholesterol and lowering LDL cholesterol.
Vitamin B12 is another of the super-charged vitamins in COR-Restor. In addition to improving the bioavailability of Nitric Oxide, it also helps maintain proper levels of Nitric Oxide by making use of excess NO in the body. As with other B vitamins it helps reduce homocysteine levels in the blood stream; thus inhibiting ADMA levels.
COR-Restor is the #1 Nitric Oxide booster because it contains the most complete formula of B vitamins available in a Nitric Oxide boosting supplement.